tinzaparin (Novo Nordisk)

**Tinzaparin** is a porcine-mucosa-derived low-molecular-weight heparin anticoagulant. It enhances antithrombin activity, producing predominantly indirect inhibition of coagulation factor Xa and, to a lesser extent, thrombin, thereby reducing thrombin generation and fibrin-clot formation. It is an established antithrombotic used for venous thromboembolism indications and is being evaluated by Alexandra Hospital in Athens in the preGO randomized study as separately administered low-molecular-weight heparin added to aspirin for prevention of preeclampsia in high-risk pregnant women. ([accessdata.fda.gov](https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020484s011lbl.pdf))

Brand names

InnohepLogiparinTinprin

Other names

tinzaparin sodium