tiotropium + formoterol + beclometasone

This is a fixed-dose combination inhaler containing three active pharmaceutical ingredients: - Tiotropium, a long-acting muscarinic antagonist (LAMA) that works by inhibiting acetylcholine at muscarinic receptors in the airways, leading to bronchodilation and improved airflow[4][5]. - Formoterol, a long-acting beta2-adrenergic receptor agonist (LABA) that stimulates beta2 receptors on bronchial smooth muscle, resulting in relaxation of airway muscles and bronchodilation[3][5]. - Beclometasone, an inhaled corticosteroid (ICS) that reduces inflammation in the airways by modulating immune cell activity and decreasing the release of inflammatory mediators. The combination is intended for maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It may also be considered for asthma management when symptoms are not adequately controlled with other therapies. The triple therapy targets both bronchoconstriction and airway inflammation to improve lung function and reduce exacerbations[5].

Brand names

InuvairSpirivaTrimbow

Other names

beclometasone/formoterol/tiotropium