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Drug intelligence / Profile preview
tiotropium bromide
- Development stage
- Preclinical
- Lead developer
- Boehringer Ingelheim
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
Tiotropium bromide is a long-acting, antimuscarinic agent (LAMA) developed by Elpen Pharma for the treatment of Chronic Obstructive Pulmonary Disease (COPD). It functions as a potent antagonist of muscarinic receptors, specifically targeting the M3 subtype located on airway smooth muscle cells. By blocking the action of acetylcholine, it prevents bronchoconstriction and promotes sustained bronchodilation. This formulation is delivered via the Elpenhaler, a multi-dose dry powder inhaler (DPI) designed to ensure consistent drug delivery to the lungs. While tiotropium bromide is a well-established therapeutic agent, this specific product represents Elpen Pharma's proprietary delivery system and formulation, which is currently in preclinical development according to company pipeline data.
- Brand names
- Elpenhaler
- Other names
- ElpenHaler4COPDElpenHaler-4COPDElpenHaler 4COPD
02
Targets
M1 (Muscarinic acetylcholine receptor M1)CHRM2 (M2)CHRM3 (M3)
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