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Tiroxime hydrochloride is a small molecule compound currently undergoing clinical trials as a potential anti-fibrotic drug. Its primary indication is for the treatment of silicosis, a lung disease caused by long-term inhalation of silica dust. The drug's mechanism of action involves intervening in the process of pulmonary fibrosis by regulating specific signaling pathways, thereby inhibiting the activation and proliferation of fibroblasts. Preclinical studies have shown its ability to significantly reduce the degree of pulmonary fibrosis in experimental animals.
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