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Tissue Repair Cells

Development stage: Phase 2
Lead developer: Vericel
Modality: Stem Cell Therapies → Cell Therapies
Administration: Intramuscular, Intraarterial, Surgical Application

Overview

Tissue Repair Cells (TRCs) are an autologous cell therapy developed by Aastrom Biosciences, Inc. They are derived from a patient's own bone marrow, which is processed and expanded using the AastromReplicell Cell Production System. This process yields a mixed population of stem and progenitor cells, including CD90+ mesenchymal stem cells and CD105+ monocytes/macrophages. TRCs are designed to promote tissue regeneration, enhance angiogenesis, improve microcirculation, and facilitate wound healing by differentiating into various tissue-specific cells and secreting cytokines and growth factors. While the term "tissue repair cells" can be used generically in scientific literature to refer to various cell types involved in healing, this entry specifically pertains to the defined drug product from Aastrom Biosciences.

Other names: Aastrom Tissue Repair Cells

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