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Titanium dioxide is an inorganic compound with the chemical formula TiO₂, occurring naturally as the minerals rutile, anatase, and brookite. It is a white, water-insoluble solid widely used as a pigment due to its brightness and high refractive index. In pharmaceuticals and consumer products, it serves primarily as a pigment for whiteness and opacity in tablets, capsules, creams, sunscreens (as a UV filter), toothpaste, food coloring (E171), cosmetics, paints, plastics, paper coatings and more[1][2][3][5][6]. In sunscreens and topical formulations it acts by absorbing or scattering ultraviolet radiation[6]. Titanium dioxide is considered inert with no direct pharmacological action; its primary function in drug products is excipient or physical barrier rather than active therapeutic agent[10].
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