Drug intelligence / Profile preview

Tivirapine

Development stage
Phase 2
Modality
Small Molecules
01

Overview

Tivirapine is a small molecule, benzodiazepine non-nucleoside reverse transcriptase inhibitor (NNRTI) that demonstrates activity against human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2), as well as simian immunodeficiency virus. It functions by inhibiting the replication of these viruses, including both wild-type and drug-resistant HIV-1 isolates. The drug has progressed to a maximum of Phase II clinical trials.

02

Targets

Human immunodeficiency virus type 1 reverse transcriptase

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