Drug intelligence / Profile preview

TJ072

Development stage
Preclinical
Lead developer
Tuojie Biotech
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

TJ072 is a preclinical-stage small interfering RNA (siRNA) therapeutic candidate being developed by Tuojie Biotech for the treatment of Alzheimer's disease. Utilizing RNA interference (RNAi) technology, TJ072 is designed to silence the expression of specific genes associated with the pathogenesis of Alzheimer's, such as those involved in the production of amyloid-beta or the aggregation of tau proteins. The program is currently in the preclinical candidate (PCC) stage and leverages Tuojie's proprietary delivery platforms for central nervous system applications.

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