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TK neoantigen vaccine

Development stage
Preclinical
Lead developer
Takis
Modality
DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

TK neoantigen vaccine is an investigational **personalized therapeutic cancer vaccine** being developed by Takis and Evvivax using a **linear DNA** vaccine approach. It is designed to encode multiple patient-specific tumor neoantigen epitopes identified from an individual patient's tumor, with the goal of inducing neoantigen-specific antitumor T-cell responses against cancer cells while sparing normal tissues. Publicly available information appears limited and largely preclinical or platform-level, but the program has been described as part of Takis and Evvivax's anti-cancer vaccine strategy for personalized oncology.

Other names
Takis TK neoantigen vaccine
02

Targets

pMHC-I (Peptide–MHC class I complex)

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