Drug intelligence / Profile preview

TKTX

Development stage
Unknown
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

TKTX is a brand of topical anesthetic products formulated primarily for temporary pain relief during cosmetic and dermatological procedures such as tattooing, laser treatments, waxing, microneedling, and minor surgical interventions. The formulations vary but commonly include local anesthetics such as lidocaine (in concentrations ranging from 7% to 22%), prilocaine (up to 7%), tetracaine (up to 3%), procaine (5%), and sometimes epinephrine/adrenaline (up to 2%). These agents act by blocking sodium channels in neuronal membranes at the site of application, thereby inhibiting nerve signal transmission and producing localized numbness. Some versions are marketed with claims of rapid onset and prolonged duration of action—numbing effects can last from three up to eight hours depending on the formulation and skin type. The products are available over-the-counter in some regions but are not approved or regulated by major health authorities like the FDA or EMA; several regulatory agencies have issued warnings regarding their unauthorized status and potential safety risks due to unverified composition[1][3][4][5][6][7][8].

Brand names
TKTXTKTX NUMBTKTX Numb BlackTKTX Numbing Cream GoldTKTX Green 75 Numbing CreamTKTX Mid Procedure Gel
02

Targets

ADRA1A (α1A)NaV (Voltage-gated sodium channels)

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