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TLANDO XR (LPCN 1111) is a next-generation, orally administered prodrug of testosterone formulated as testosterone tridecanoate, developed to provide once-daily testosterone replacement therapy (TRT) for male hypogonadism. Utilizing Lipocine’s proprietary solubilization technology (Lip'ral), it is designed for improved systemic absorption and convenience over existing therapies. Clinical studies have shown favorable safety, tolerability, and pharmacokinetic profiles, with no drug-related severe or serious adverse events detected. TLANDO XR represents an advancement over prior formulations, aiming to mitigate the limitations and transfer risks associated with topical testosterone replacement options.
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