Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
TMC647055 + telaprevir
- Development stage
- Unknown
- Lead developer
- Janssen Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
TMC647055 + telaprevir is a **combination therapy** developed for the treatment of chronic hepatitis C virus (HCV) infection. **TMC647055** is a potent, selective, nonnucleoside small-molecule inhibitor of the HCV NS5B RNA-dependent RNA polymerase, binding to the NNI-1 allosteric site, thus inhibiting viral RNA replication. **Telaprevir** is a small-molecule inhibitor of the HCV NS3/4A protease, which is critical for viral polyprotein processing and RNA replication. This combination targets two different steps in the HCV replication cycle and is being investigated for synergistic antiviral efficacy and suppression of resistant viral mutations.
02
Targets
NS5B (Hepatitis C virus non-structural protein 5B (NS5B) RNA-dependent RNA polymerase)NS3/4A (Hepatitis C virus nonstructural protein 3/4A serine protease)
Beyond the preview
Go deeper on TMC647055 + telaprevir.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on TMC647055 + telaprevir.