Drug intelligence / Profile preview

TML-NAL-22

Development stage
Preclinical
Lead developer
Themis Medicare
Modality
Small Molecules
Administration
Injection
01

Overview

TML-NAL-22 is a preclinical pharmaceutical candidate being developed by Themis Medicare. It is a ready-to-use (RTU) injectable formulation of a proton-pump inhibitor (PPI). As a PPI, the drug's primary mechanism of action involves the irreversible inhibition of the gastric H+/K+-ATPase (proton pump) in the parietal cells of the stomach, which is the final step in gastric acid secretion. Themis Medicare specializes in Novel Drug Delivery Systems (NDDS) and specialized injectable formulations, and TML-NAL-22 is designed as a stable, ready-to-use injection to simplify administration and reduce preparation errors in clinical settings. It is currently in the preclinical stage of development for indications requiring rapid or parenteral acid suppression.

Other names
TML-NAL-22-Themis Medicare-Ready to use injection-injection-Proton-Pump InhibitorTML-NAL22-Themis Medicare-Ready to use injection-injection-Proton-Pump InhibitorTML-NAL 22-Themis Medicare-Ready to use injection-injection-Proton-Pump Inhibitor
02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)

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