Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
TMX ET
- Development stage
- Phase 4
- Lead developer
- Ind Blues Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
TMX ET is a combination oral tablet containing the antifibrinolytic agent tranexamic acid and the hemostatic agent ethamsylate (etamsylate). Developed and marketed by Ind Blues Pharma, it is primarily indicated for the treatment of heavy menstrual bleeding (menorrhagia) and dysfunctional uterine bleeding. Tranexamic acid works by reversibly binding to lysine-binding sites on plasminogen, preventing its activation to plasmin and thereby inhibiting fibrinolysis (the breakdown of blood clots). Ethamsylate acts on primary hemostasis by improving platelet adhesiveness, promoting platelet aggregation, and restoring capillary resistance, partly through the inhibition of prostacyclin (PGI2) synthesis. Together, the two active ingredients provide a synergistic effect to control excessive bleeding and reduce blood loss.
- Brand names
- TMX ETTMX-ET
- Other names
- etamsylate + tranexamic acidethamsylate + tranexamic acidtranexamic acid + etamsylatetranexamic acid + ethamsylate
02
Targets
PLG (Plasminogen)PTGIS (Prostacyclin synthase)
Beyond the preview
Go deeper on TMX ET.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on TMX ET.