Drug intelligence / Profile preview

TNV108

Development stage
Preclinical
Lead developer
Tenvie Therapeutics
Modality
Small Molecules
01

Overview

TNV108 is a **small molecule** SARM1 inhibitor being developed by **Tenvie Therapeutics** for **peripheral neuropathies**. It is described as a **peripherally restricted allosteric inhibitor** of Sterile Alpha and TIR Motif Containing 1, a design intended to limit central nervous system penetration while modulating SARM1-driven axonal degeneration biology in the peripheral nervous system. Based on the provided context, TNV108 is in **preclinical development**.

02

Targets

SARM1

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