Drug intelligence / Profile preview

TNX-3700

Development stage
Preclinical
Lead developer
Tonix Pharmaceuticals
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Parenteral
01

Overview

TNX-3700 is a preclinical mRNA vaccine candidate being developed by Tonix Pharmaceuticals in collaboration with Kansas State University for the prevention of COVID-19. The vaccine utilizes a novel Zinc Nanoparticle (ZNP) formulation technology as a delivery vehicle for mRNA encoding the SARS-CoV-2 spike protein. This ZNP technology is designed as a more stable alternative to the Lipid Nanoparticle (LNP) technology used in existing mRNA vaccines, potentially eliminating the need for ultra-cold chain storage and transport, thereby facilitating easier and more rapid global deployment. The program is currently in the preclinical research stage, involving studies in tissue culture and animal models.

02

Targets

SARS-CoV-2 spike

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