Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
tocopheryl phosphate
- Development stage
- Unknown
- Lead developer
- Avecho Biotechnology
- Modality
- Small Molecules
- Administration
- Oral, Topical, Transdermal
01
Overview
Tocopheryl phosphate, specifically the Tocopheryl Phosphate Mixture (TPM®), is a proprietary drug delivery platform developed by Phosphagenics (now Avecho Biotechnology). It consists of a mixture of mono-tocopheryl phosphate and di-tocopheryl phosphate, which are phosphorylated derivatives of Vitamin E. TPM acts as a lipid-based delivery system that enhances the solubility and absorption of poorly water-soluble drugs across biological membranes, including the skin and gastrointestinal tract. Beyond its role as a carrier, it exhibits intrinsic anti-inflammatory properties by modulating pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α. It has been investigated in various clinical applications, including transdermal pain management (e.g., with oxycodone), topical treatments for acne, and oral delivery of nutrients and pharmaceuticals.
- Brand names
- Vital ET
- Other names
- Tocopheryl Phosphate Mixturealpha-tocopheryl phosphatedi-alpha-tocopheryl phosphateTPT2PT-2PT 2P
02
Targets
IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)IL8 (C-X-C Motif Chemokine Ligand 8)TNFA (Tumor necrosis factor alpha (soluble))Biological membrane
Beyond the preview
Go deeper on tocopheryl phosphate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on tocopheryl phosphate.