Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
tocopheryl phosphate mix
- Development stage
- Unknown
- Lead developer
- Avecho Biotechnology
- Modality
- Small Molecules
- Administration
- Oral, Topical
01
Overview
Tocopheryl phosphate mix (TPM) is a proprietary lipid-based drug delivery technology developed by Avecho Biotechnology (formerly Phosphagenics Limited). It is composed of two phosphorylated forms of Vitamin E: mono-alpha-tocopheryl phosphate (TP) and di-alpha-tocopheryl phosphate (T2P). TPM self-assembles into vesicular nanostructures that encapsulate and solubilize poorly soluble active pharmaceutical ingredients (APIs), thereby enhancing their absorption and bioavailability across biological membranes. In clinical development, TPM has been evaluated as an oral delivery enhancer for Vitamin D to improve systemic exposure in patients with vitamin D deficiency. The technology is also utilized in topical and injectable formulations for various other therapeutic applications, including pain management and dermatology.
- Brand names
- Vital ET
- Other names
- alpha-tocopheryl phosphate and di-alpha-tocopheryl phosphate mixture
02
Targets
VDR (Vitamin D receptor)
Beyond the preview
Go deeper on tocopheryl phosphate mix.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on tocopheryl phosphate mix.