Drug intelligence / Profile preview

Tocovid SupraBio + pentoxifylline

Development stage
Unknown
Lead developer
Hovid
Modality
Small Molecules
Administration
Oral
01

Overview

A combination therapy consisting of Tocovid SupraBio (a bioenhanced full spectrum palm tocotrienol complex) and pentoxifylline. This combination was investigated for treating long-term gastrointestinal adverse effects following pelvic radiotherapy for cancer. Preclinical data suggested that combined gamma-tocotrienol with pentoxifylline could ameliorate radiotherapy-induced gastrointestinal damage. The treatment regimen consisted of Tocovid SupraBio 200 mg and pentoxifylline 400 mg, both taken orally twice daily.

02

Targets

PDE (Phosphodiesterase family)ADORA2B (Adenosine A2B receptor)

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