Drug intelligence / Profile preview

Tokyo Inst. of Technology CAIX compound 3

Development stage
Unknown
Lead developer
Institute of Science Tokyo
01

Overview

Tokyo Inst. of Technology CAIX compound 3: sourced facts only. name: "Mechanistic studies revealed that compound 3 not only induced CAIX-selective light inactivation via singlet oxygen but also induced cell membrane damage, resulting in an anti-tumor effect." [PMID:38810709]; target: "Mechanistic studies revealed that compound 3 not only induced CAIX-selective light inactivation via singlet oxygen but also induced cell membrane damage, resulting in an anti-tumor effect." [PMID:38810709]; developer: "Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8501, Japan." [PMID:38810709]; stage: "In vivo studies of CAIX-targeting MT-PDT revealed that treatment with compound 3 followed by light irradiation exhibited remarkable anti-tumor activity, leading to tumor degeneration and necrosis." [PMID:38810709]

02

Targets

CA9 (Carbonic anhydrase IX)

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