Drug intelligence / Profile preview

tolmetin

Development stage
Approved
Lead developer
Johnson & Johnson
Modality
Small Molecules
Administration
Oral
01

Overview

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and relieve symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis in children aged two years and older. It works primarily by inhibiting prostaglandin synthetase (cyclooxygenase), thereby reducing the synthesis of prostaglandins that mediate inflammation, pain, and fever. Tolmetin does not cure underlying disease but helps control symptoms as long as it is taken. It is available in oral capsule and tablet forms[1][2][3][4][5].

Brand names
TolectinTolectin DSTolectin 600Tolectin600Tolectin-600
Other names
tolmetinatolmétinetolmetinotolmetinum1-methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid1-methyl-5-p-toluoylpyrrole-2-acetic acid5-(p-toluoyl)-1-methylpyrrole‑2‑acetic acid
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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