Drug intelligence / Profile preview

Tolumar

Development stage
Unknown
Lead developer
Ghimas
Modality
Small Molecules
Administration
Oral
01

Overview

Tolumar is a nutraceutical supplement developed by the Italian company Ghimas S.p.A., specifically formulated to support joint health and manage symptoms of degenerative joint conditions such as osteoarthritis. The product contains a synergistic combination of **glucosamine sulfate**, **chondroitin sulfate**, and **Vitamin C** (ascorbic acid). Glucosamine and chondroitin are fundamental components of articular cartilage, serving as precursors for the synthesis of glycosaminoglycans and proteoglycans, which maintain the elasticity and shock-absorbing properties of the joint matrix. Vitamin C acts as an essential cofactor for the enzyme prolyl hydroxylase, which is required for the stabilization of collagen fibers. By providing these structural building blocks and supporting enzymatic repair processes, Tolumar aims to preserve cartilage integrity and reduce the progression of joint wear.

Brand names
Tolumar
02

Targets

HIF axis (Hypoxia signaling family)ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)ELANE (Human Neutrophil Elastase)

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