Drug intelligence / Profile preview

Tongbi Tuomin Gao

Development stage
Unknown
Lead developer
Renhe Pharmacy
Administration
Intranasal
01

Overview

Tongbi Tuomin Gao is a topical herbal formulation widely utilized in China for the symptomatic relief of allergic rhinitis, chronic rhinitis, and nasal congestion. The product typically functions through a combination of aromatic compounds and Traditional Chinese Medicine (TCM) extracts. Key active ingredients often include menthol and camphor, which act on TRPM8 and TRPV1 receptors to provide a cooling sensation and alleviate the perception of airflow obstruction. Additionally, botanical components such as *Magnolia biondii* (Xin Yi), *Xanthium sibiricum* (Cang Er Zi), and *Centipeda minima* (E Bu Shi Cao) are included for their purported anti-inflammatory and anti-allergic properties, potentially inhibiting mast cell degranulation and local histamine release. While frequently marketed as a medical device or health product (sanitation grade) by companies like Renhe and Xiuzheng, it remains a staple in the management of minor upper respiratory allergies and congestion in the region.

Brand names
Tongbi Tuomin GaoRenhe Tongbi Tuomin GaoXiuzheng Tongbi Tuomin Gao
Other names
通鼻脱敏膏Nasal Clearing and Desensitizing OintmentTongbi Tuomin Nasal Ointment
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)HRH1 (Histamine H1 Receptor)

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