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Tonghua Liyan Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by the Yueyang Integrated Traditional Chinese and Western Medicine Hospital, affiliated with the Shanghai University of Traditional Chinese Medicine. It is primarily investigated for the treatment of gastroesophageal reflux disease (GERD)-associated pharyngitis, particularly in patients who have failed to respond to standard proton pump inhibitor (PPI) therapy. The decoction is designed to harmonize the stomach and benefit the throat, addressing the underlying TCM patterns of reflux-induced laryngeal symptoms. In clinical trial settings, it has been evaluated in randomized, controlled studies to assess its efficacy and safety compared to standard treatments like rabeprazole.
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