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Tongjingning is a traditional Chinese medicine (TCM) formulation used primarily for the treatment of primary dysmenorrhea and menstrual pain. It is available in various forms such as granules and capsules. The formula typically contains multiple herbal ingredients; one identified active component is paeoniflorin, which is derived from Paeonia species[3]. Clinical studies have evaluated the efficacy of Tongjingning Granules combined with ibuprofen for alleviating primary dysmenorrhea, suggesting it may help regulate immune function and reduce pain[5][7]. The mechanism of action appears to involve modulation of inflammatory mediators and improvement in uterine microcirculation, though precise molecular targets are not fully characterized.
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