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tongluo zhitong liquid
- Development stage
- Unknown
- Lead developer
- Gansu Provincial Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tongluo, specifically referring to the **Tongluo Zhitong** (通络止痛) series of preparations developed by the **Gansu Provincial Hospital of Traditional Chinese Medicine**, is a Traditional Chinese Medicine (TCM) treatment used for chronic musculoskeletal pain. The most prominent form is the **Tongluo Zhitong Liquid**, an oral hospital preparation indicated for conditions such as chronic low back pain, sciatica, lumbar disc herniation, lumbar muscle strain, knee arthritis, and cervical spondylosis. The formulation is designed to "dredge the meridians" and "unblock the collaterals" to improve blood circulation and alleviate pain. Pharmacologically, these preparations are thought to exert anti-inflammatory and analgesic effects by inhibiting pro-inflammatory cytokines like TNF-α, IL-1β, and IL-6, and modulating inflammatory enzymes such as COX-2. It is a registered hospital preparation (院内制剂) widely utilized within the Gansu provincial medical system.
- Brand names
- Tongluo
- Other names
- Tongluo Zhitong YeTongluo Zhitong CapsuleTongluo Zhitong LiquidTongluo Zhitong PlasterTongluo Liquid
02
Targets
IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))
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