Drug intelligence / Profile preview

Tongluohuoxue Formula

Development stage
Preclinical
Lead developer
First Affiliated Hospital of Guangzhou University of Chinese Medicine
Administration
Topical
01

Overview

Tongluohuoxue Formula is a Traditional Chinese Medicine (TCM) herbal formula. Its name, which translates to "unblocking collaterals and activating blood circulation," reflects its traditional therapeutic principles. The formula is currently under investigation in a multicenter, double-blind, placebo-controlled clinical trial for the prevention and management of paclitaxel-induced peripheral neuropathy. In this trial, it is administered topically.

Other names
Tongluo Huoxue FormulaTongluo Huoxue DecoctionTongluo Huoxue Recipe
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IKBKE (IκB kinase epsilon)NF-κBIL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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