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Tongmai Jiangzhuo granules
- Development stage
- Phase 3
- Lead developer
- First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Tongmai Jiangzhuo granules is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. It is primarily investigated for the early intervention of preclinical atherosclerosis. The formulation is designed to "unblock vessels" and "reduce turbidity," targeting cardiovascular risk factors and the progression of carotid intima-media thickness (CIMT). In clinical studies, it is evaluated as an adjunct to lifestyle interventions to improve cardiovascular outcomes and metabolic markers. It has been studied in Phase 3 clinical trials in China.
- Other names
- Tongmai Jiangzhuo Keli
02
Targets
ABCA1 (ATP-binding cassette transporter A1)CD36 (CD36 antigen)NR1H3 (Liver X receptor beta)PPARG (Peroxisome proliferator-activated receptor gamma)
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