Drug intelligence / Profile preview

Tongmai Jiangzhuo granules

Development stage
Unknown
Lead developer
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Tongmai Jiangzhuo granules is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. It is primarily investigated for the early intervention of preclinical atherosclerosis. The formulation is designed to "unblock vessels" and "reduce turbidity," targeting cardiovascular risk factors and the progression of carotid intima-media thickness (CIMT). In clinical studies, it is evaluated as an adjunct to lifestyle interventions to improve cardiovascular outcomes and metabolic markers. It has been studied in Phase 3 clinical trials in China.

Other names
Tongmai Jiangzhuo Keli
02

Targets

CD36 (CD36 antigen)PPARG (Peroxisome proliferator-activated receptor gamma)ABCA1 (ATP-binding cassette transporter A1)NR1H3 (Liver X receptor beta)

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