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Tongning Gel
- Development stage
- Unknown
- Lead developer
- Lianyungang Kanion
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Tongning Gel is a topical Traditional Chinese Medicine (TCM) formulation developed by Jiangsu Kanion Pharmaceutical for the treatment of knee osteoarthritis. It is designed to provide localized analgesic and anti-inflammatory effects directly at the site of joint pain. The gel formulation facilitates the delivery of active herbal constituents, which typically include extracts from *Corydalis yanhusuo*, *Olibanum* (Frankincense), and *Myrrha* (Myrrh). These components are traditionally used to improve blood circulation, resolve blood stasis, and alleviate pain associated with degenerative joint diseases. Tongning Gel has undergone Phase 3 clinical trials in China to evaluate its efficacy in reducing pain and improving physical function in patients with knee osteoarthritis, positioning it as a non-systemic therapeutic option for chronic joint pain management.
- Brand names
- Tongning Gel
- Other names
- Tongning Ningjiao痛宁凝胶
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGE2 (Prostaglandin E2)
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