Drug intelligence / Profile preview

Tongyang Huoxue Decoction

Development stage
Unknown
Lead developer
Guang'anmen Hospital
Administration
Oral
01

Overview

Tongyang Huoxue Decoction is a Traditional Chinese Medicine (TCM) herbal formulation developed by researchers at Guang'anmen Hospital and the China Academy of Chinese Medical Sciences. It is primarily investigated for the treatment of sick sinus syndrome (SSS), a condition characterized by sinoatrial node dysfunction leading to abnormal heart rhythms. Based on TCM principles, the decoction is formulated to warm yang and promote blood circulation (huoxue), aiming to improve heart rate and alleviate clinical symptoms such as dizziness, fatigue, and palpitations. In clinical evaluations, the decoction has been administered in a granule form and compared against standard pharmacological treatments like theophylline sustained-release tablets to assess its efficacy and safety in improving cardiac conduction.

Other names
Tongyang Huoxue Granules
02

Targets

SERCA2VDAC1 (Hexokinase 2–voltage-dependent anion channel 1 complex)TUBB (Tubulin (alpha and beta subunits))

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