Drug intelligence / Profile preview

topical apremilast nanoemulsion

Development stage
Unknown
Lead developer
Assiut University
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical
01

Overview

Topical apremilast nanoemulsion is an investigational nanoparticle-based formulation of the phosphodiesterase 4 (PDE4) inhibitor apremilast. Developed by researchers at Assiut University, specifically at the Assiut International Center of Nanomedicine, this formulation is designed for the treatment of localized mild to moderate plaque psoriasis. By utilizing a nanoemulsion delivery system, the drug aims to enhance skin penetration and local therapeutic efficacy while minimizing the systemic adverse effects typically associated with oral apremilast administration. In clinical studies, it is being evaluated both as a monotherapy and in combination with topical corticosteroids to improve tissue-level responses and reduce corticosteroid-related side effects.

Other names
Apremilast Nanoformula 0.3%topical apremilast nanoparticlesapremilast nano-formulationApremilast Nanoformula 0.3٪
02

Targets

PDE4 (Phosphodiesterase 4A1)

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