Drug intelligence / Profile preview

Total Saponins from Wild-Simulated American Ginseng

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

TSW (Total Saponins from Wild-Simulated American Ginseng) is a natural extract derived from wild-simulated American ginseng. It has demonstrated protective effects against chronic obstructive pulmonary disease (COPD) by alleviating oxidative stress and inflammatory responses. TSW has shown a stronger therapeutic effect compared to total saponins from field-grown American ginseng (TSF). Its efficacy is attributed to a combination of active compounds, including ginsenoside Rgl, Rc, oleanolic acid, notoginsenoside R1, Fe, and silphioside B, which contribute to its anti-COPD activity.

02

Targets

Misfolded SOD1AST (Glutamate oxaloacetate transaminase 1)ROS1 (Proto-oncogene tyrosine-protein kinase ROS)CKB (Creatine kinase B-type)LDH (L-lactate dehydrogenase A chain)

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