Drug intelligence / Profile preview

TOTUM-070

Development stage
Unknown
Lead developer
Valbiotis
Administration
Oral
01

Overview

TOTUM-070 is a plant-derived active substance developed by Valbiotis, specifically designed to reduce LDL-cholesterol levels in individuals with mild-to-moderate hypercholesterolemia. It is a patented combination of five plant extracts that aims to provide a non-drug alternative or complement for cardiovascular risk management. The product's efficacy was evaluated in the Phase 2 HEART clinical trial, which demonstrated a significant reduction in blood LDL-cholesterol levels compared to placebo. TOTUM-070 is positioned within the Nutrition Health space, targeting the prevention of metabolic and cardiovascular diseases through a multi-targeted approach to lipid metabolism.

Brand names
ValbiotisPRO CholesterolValbiotis PRO Cholesterol
Other names
Lipidrive
02

Targets

NPC1L1 (Niemann-pick C1-Like 1 transporter)

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