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Toutongning
- Development stage
- Phase 4
- Lead developer
- Buchang Pharmaceuticals
- Administration
- Oral
01
Overview
Toutongning is a Traditional Chinese Medicine (TCM) formulation, typically administered as a capsule, used primarily for the treatment of migraine, tension-type headaches, and trigeminal neuralgia. Developed and manufactured by companies such as Shaanxi Buchang Pharmaceuticals, it is composed of several herbal and animal-derived ingredients, including *Arisaema cum Bile*, *Gastrodia elata*, *Ligusticum chuanxiong*, and *Angelica dahurica*. The formulation is designed to "dispel wind, resolve phlegm, and activate blood circulation" according to TCM principles. Clinical studies, including those conducted by the Chinese PLA General Hospital, have evaluated its efficacy in reducing the frequency and severity of migraine attacks, potentially through mechanisms involving the regulation of neurotransmitters and anti-inflammatory pathways.
- Brand names
- Toutongning
- Other names
- Toutongning capsuleToutongning Jiaonang
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NOS2 (Nitric Oxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))5-HT (Serotonin receptors)Calcitonin gene-related peptide type 1 receptor
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