Drug intelligence / Profile preview

TPR100

Development stage
Preclinical
Lead developer
Futura Medical
Modality
Small Molecules
Administration
Topical
01

Overview

**TPR100** is a topical diclofenac gel developed by Futura Medical using their proprietary **DermaSys® transdermal technology**, which enhances skin permeation and enables rapid delivery of diclofenac, a non-steroidal anti-inflammatory drug (NSAID), to provide sustained pain relief for up to 12 hours. Diclofenac inhibits **cyclooxygenase (COX) enzymes**, reducing prostaglandin synthesis to alleviate pain and inflammation. It is designed for treating pain associated with sprains, strains, bruises, soft tissue rheumatism, and muscle/soft tissue conditions, with improved permeation compared to market-leading diclofenac gels like Pennsaid and Voltaren, potentially offering faster onset, deeper penetration, or longer duration while minimizing systemic absorption and side effects.

02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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