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TQA3605 is an orally available small molecule drug under development for the treatment of chronic hepatitis B virus (HBV) infection. It acts as a capsid protein inhibitor, targeting the HBV core/capsid protein to disrupt viral replication. The drug is being developed by Chia Tai Tianqing Pharmaceutical Group and has reached Phase II clinical trials in China, both as monotherapy and in combination with nucleos(t)ide analogues. Its primary indication is chronic hepatitis B, where it aims to improve virological response rates compared to standard therapy[1][2][3].
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