Drug intelligence / Profile preview

TQB3558

Development stage
Phase 1
Lead developer
Chia Tai-Tianqing Pharmaceutical Group
Modality
Small Molecules
Administration
Oral
01

Overview

TQB3558 is an orally available small molecule inhibitor of tropomyosin receptor kinases (Trk), including TrkA, TrkB, and TrkC. It is being developed for its potential antineoplastic activity and as a treatment for cancer pain. By inhibiting the activity of these kinases, which are involved in the growth and survival of certain cancer cells as well as pain signaling pathways, TQB3558 may suppress tumor progression and alleviate cancer-related pain. The drug is under development by Chia Tai Tianqing Pharmaceutical Group.

Other names
TRK inhibitor TQB3558
02

Targets

NTRK1 (Tropomyosin-related receptor kinase A)NTRK3 (Tropomyosin receptor kinase C)NTRK2 (Tropomyosin-related kinase receptor type B)

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