Drug intelligence / Profile preview

TQC3301

Development stage
Unknown
Lead developer
Chia Tai-Tianqing Pharmaceutical Group
Modality
Small Molecules
Administration
Inhalation
01

Overview

TQC3301 is an inhaled formulation of budesonide, a potent synthetic glucocorticoid corticosteroid, being developed by Chia Tai Tianqing for the treatment of asthma. As a glucocorticoid receptor agonist, budesonide exerts anti-inflammatory effects by binding to the glucocorticoid receptor, which subsequently inhibits the expression of pro-inflammatory genes and reduces the recruitment of inflammatory cells in the airways. TQC3301 is specifically designed as an inhalation spray, and its clinical development includes Phase 1 studies evaluating its safety, pharmacokinetics, and lung deposition in healthy volunteers, often in comparison to established budesonide dry powder inhalers.

Other names
budesonide inhalation spray
02

Targets

GR (Glucocorticoid receptor)

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