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Traditional Chinese medicine formula No.2 is an individualized herbal formulation developed by the Yunnan Provincial Hospital of Traditional Chinese Medicine for the treatment of rheumatoid arthritis. In clinical trial settings, it is evaluated as an adjunctive therapy alongside conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) such as methotrexate and leflunomide. The therapeutic objective is to leverage the immunomodulatory and anti-inflammatory properties of the TCM herbs to facilitate the tapering and successful discontinuation of glucocorticoids (e.g., prednisone) in patients with stable disease, thereby reducing the long-term side effects associated with steroid use.
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