Drug intelligence / Profile preview

tranexamic acid + etamsylate

Development stage
Phase 4
Lead developer
Biocon
Modality
Small Molecules
Administration
Oral
01

Overview

Albufree TX is a fixed-dose combination pharmaceutical product containing tranexamic acid and etamsylate, primarily utilized in the management of abnormal uterine bleeding and other conditions characterized by excessive blood loss. Tranexamic acid is a synthetic lysine derivative that acts as an antifibrinolytic by competitively inhibiting the activation of plasminogen to plasmin, thereby stabilizing fibrin clots and preventing their premature degradation. Etamsylate (also known as ethamsylate) is a hemostatic agent that enhances platelet adhesion and restores capillary resistance, providing a synergistic effect alongside tranexamic acid to reduce both the duration and volume of hemorrhage. The brand was originally part of Biocon's branded formulations portfolio in India before the division's acquisition by Eris Lifesciences.

Brand names
Albufree TX
Other names
Albufree-TXtranexamic acid + ethamsylate
02

Targets

PLG (Plasminogen)SELP (P-selectin)

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