Drug intelligence / Profile preview

tranexamic acid + misoprostol

Development stage
Phase 4
Lead developer
PATH
Modality
Small Molecules
Administration
Intravenous, Sublingual
01

Overview

A combination of tranexamic acid, an antifibrinolytic agent that inhibits plasminogen activation, and misoprostol, a prostaglandin E1 analog that stimulates uterine contractions. This combination is primarily used to prevent and treat postpartum hemorrhage, particularly in high-risk patients undergoing cesarean delivery or other obstetric procedures. Clinical studies show it significantly reduces blood loss compared to oxytocin alone or carbetocin.

Other names
misoprostol and tranexamic acidtranexamic acid + misoprostol
02

Targets

PLG (Plasminogen)

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