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tranexamic acid + misoprostol
- Development stage
- Unknown
- Lead developer
- PATH
- Modality
- Small Molecules
- Administration
- Intravenous, Sublingual
01
Overview
A combination of tranexamic acid, an antifibrinolytic agent that inhibits plasminogen activation, and misoprostol, a prostaglandin E1 analog that stimulates uterine contractions. This combination is primarily used to prevent and treat postpartum hemorrhage, particularly in high-risk patients undergoing cesarean delivery or other obstetric procedures. Clinical studies show it significantly reduces blood loss compared to oxytocin alone or carbetocin.
- Other names
- misoprostol and tranexamic acidtranexamic acid + misoprostol
02
Targets
PLG (Plasminogen)
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