TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE

TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE is a synthetic peptide or peptidomimetic characterized by its complex chemical structure, which includes a guanidinomethyl-cyclohexane moiety, D-cyclohexylalanyl, L-azetidine-2-yl, D-tyrosinyl, and L-homoargininamide residues. The presence of guanidinium groups (from guanidinomethyl and homoargininamide) suggests potential interactions with negatively charged biological sites, often found in enzyme active sites or receptor binding pockets. The L-azetidine-2-yl residue is a proline analog, which can introduce conformational constraints and influence the secondary structure and stability of the peptide, thereby affecting its biological activity and interaction with target molecules. While the specific biological activity, primary indication, or developer of this compound are not readily available in public databases, its intricate design is typical of compounds developed for research into protein-ligand interactions, enzyme inhibition, or receptor modulation.

Other names

(2S)-N-[(2R)-1-[[(2S)-1-amino-6-(diaminomethylideneamino)-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-1-[(2R)-3-cyclohexyl-2-[[4-[(diaminomethylideneamino)methyl]cyclohexanecarbonyl]amino]propanoyl]azetidine-2-carboxamide