Drug intelligence / Profile preview

TransipegLib

Development stage
Phase 4
Lead developer
Recordati
Modality
Small Molecules
Administration
Oral
01

Overview

**TransipegLib** is an iso-osmotic laxative formulation containing **5.9 g macrogol 3350 (polyethylene glycol 3350)** per sachet, combined with electrolytes (sodium chloride, anhydrous sodium sulfate, potassium chloride, sodium bicarbonate) for the treatment of **occasional constipation in adults**. It works by retaining water in the intestinal lumen through hydrogen bonding, increasing stool hydration and volume to promote bowel movements, with effects typically within **24-48 hours**. Lemon-flavored powder for oral solution, dosed 1-2 sachets daily (dissolved in 100 ml water), not exceeding one week without medical advice; contains notable excipients including **290 mg sodium**, **40 mg potassium**, and **aspartame** (contraindicated in phenylketonuria).[1][2][4]

Brand names
TransipegLibTransipeg
Other names
PEG3350+Epolyethylene glycol 3350 + electrolytes
02

Targets

Intestinal luminal water and osmotic gradient

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