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Translational Therapeutics eIF4E small molecule
- Development stage
- Unknown
- Lead developer
- Translational Therapeutics
- Modality
- Small Molecules
- Administration
- Intraperitoneal
01
Overview
A **preclinical to early clinical-stage small-molecule antineoplastic program** from **Translational Therapeutics** designed to inhibit or modulate the oncogenic translation factor **eukaryotic translation initiation factor 4E** and disrupt its reported \"gating\" role in malignant mRNA translation. The program is being positioned for **eIF4E-driven cancers**, described by the company as **4E cancers**, and has been presented as **IND-ready** and preparing for initiation of a **Phase 1/2** study in an orphan oncology setting. No distinct non-proprietary name, code name, brand name, formulation, or route of administration was identified from the provided materials.
- Other names
- Translational Therapeutics eIF4E small moleculeeIF4E small moleculeeIF-4E small moleculeeIF 4E small molecule4E cancers small molecule
02
Targets
EIF4E (Eukaryotic translation initiation factor 4E)
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