Transtec

Transtec is a transdermal delivery system for buprenorphine, developed and manufactured by Grünenthal GmbH for the treatment of moderate to severe chronic pain, including cancer pain and severe pain unresponsive to non-opioid analgesics. As a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor, buprenorphine provides effective analgesia while exhibiting a "ceiling effect" on respiratory depression, which enhances its safety profile relative to full opioid agonists like morphine. The Transtec patch is designed for sustained release, typically applied every 72 to 96 hours, ensuring stable therapeutic plasma levels and improving patient adherence. It is widely utilized in clinical practice for patients requiring continuous, long-term opioid therapy.

Brand names

Transtec

Other names

buprenorphine transdermal patch