Drug intelligence / Profile preview

Transversus Abdominis Plane Block

Development stage
Preclinical
Lead developer
Medipol Üniversitesi
Modality
Small Molecules
Administration
Perineural
01

Overview

Transversus Abdominis Plane Block (TAPB) is a regional anesthesia technique used to provide analgesia to the anterolateral abdominal wall. In the clinical study conducted by Medipol University, TAPB is performed under ultrasound guidance by injecting a local anesthetic, specifically bupivacaine, into the neurovascular plane between the internal oblique and transversus abdominis muscles. This procedure is primarily indicated for managing postoperative pain following abdominal surgeries, such as laparoscopic cholecystectomy. By blocking the sensory nerves of the anterior abdominal wall (T6 to L1), TAPB aims to improve patient recovery scores and reduce the requirement for systemic rescue opioids and their associated side effects.

Other names
TAP blockUltrasound-Guided Transversus Abdominis Plane Block
02

Targets

NaV (Voltage-gated sodium channels)

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