Drug intelligence / Profile preview

transversus abdominus plane-Ain Shams Maternity Hospital-postoperative pain

Development stage
Unknown
Lead developer
Ain Shams University Maternity Hospital
Modality
Small Molecules
Administration
Regional Block
01

Overview

A clinical trial intervention conducted at Ain Shams Maternity Hospital evaluating a Modified Surgeon Assisted Bilateral Transversus Abdominis Plane (TAP) block for postoperative pain management after cesarean section. The technique involves the injection of bupivacaine, a local anesthetic, into the fascial plane between the internal oblique and transversus abdominis muscles. By blocking the T6-L1 nerve branches that provide sensation to the anterior abdominal wall, the intervention aims to provide effective regional analgesia, reduce the requirement for systemic opioids, and minimize associated side effects such as nausea and respiratory depression.

Other names
Modified Surgeon Assisted Bilateral Transversus Abdominis Plane blockModified Surgeon Assisted Bilateral TAP blockTAP block with bupivacaine
02

Targets

NaV (Voltage-gated sodium channels)

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