Drug intelligence / Profile preview

transversus thoracic muscle plane block

Development stage
Unknown
Lead developer
Eric Albrecht
Modality
Small Molecules
Administration
Injection
01

Overview

The transversus thoracic muscle plane block (TTMPB) is a regional anesthesia technique being investigated by Eric Albrecht for its efficacy in managing postoperative pain following elective open-heart surgery. The procedure involves the ultrasound-guided bilateral injection of bupivacaine (0.375%) into the fascial plane between the internal intercostal muscle and the transversus thoracic muscle, typically at the level of the 4th thoracic vertebra. This block targets the anterior cutaneous branches of the intercostal nerves (T2-T6), providing analgesia to the sternum and anterior chest wall. The intervention is evaluated as an adjunct to standard multimodal analgesia protocols to reduce opioid consumption and facilitate early recovery.

Other names
TTMPBTransversus thoracic muscle plane block with bupivacaine
02

Targets

NaV (Voltage-gated sodium channels)

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