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trapicolast
- Development stage
- Preclinical
- Lead developer
- Adnexus Biotechnologies
01
Overview
Trapicolast is an unapproved, AI-discovered antimalarial product reported by **Adnexus Biotechnologies**. The company describes it as a combination of two undisclosed development compounds, ADX1 and ADX2, identified using its Sutra AI platform. According to the company release, the combination is intended to inhibit *Plasmodium* apicoplast DNA synthesis and vesicular trafficking, with the goal of addressing resistance to established antimalarial therapies, including artemisinin-based regimens. The public announcement does not disclose the chemical structures, specific molecular targets, formulation, route of administration, clinical-stage data, or a patent application number. ([biospace.com](https://www.biospace.com/press-releases/adnexus-biotechnologies-inc-unveils-ai-driven-malaria-cure-with-trapicolast))
- Other names
- trapicolast
02
Targets
apPol (Apicoplast DNA polymerase)
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