Drug intelligence / Profile preview

Travesol

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous
01

Overview

Travesol is a 10% amino acid solution primarily utilized as a component of parenteral nutrition to provide a source of nitrogen and essential amino acids for patients who cannot receive adequate oral or enteral intake. In the context of clinical research, specifically at Penn State Health Milton S. Hershey Medical Center, it is being evaluated for its potential to prevent acute kidney injury (AKI) in patients undergoing elective cardiac surgery with cardiopulmonary bypass. The proposed mechanism for this protective effect involves the induction of renal vasodilation and an increase in the glomerular filtration rate (GFR), which enhances the kidney's resilience to ischemic stress during surgery. It is administered via intravenous infusion.

Brand names
TravesolTravasol
Other names
amino acid injectionamino acids
02

Targets

SERPINA1 (Alpha-1-antitrypsin)

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